Thesis Statements - 1159 Words

Jacob Dearing APUSH 2/20/13 Thesis assignment 1. The American city was changed drastically in the first half of the 20th century with the beginnings of the industrial revolution and the ongoing flow of foreigners into an already crowded United States. 2. Many men around the time of the 20th century had parts in the progressive era reform and were influential in politics and majorly through social conditions. 3. Progressive era reforms were not that prominent in the late 19th century and the early 20th century, although they were a part of the workings of that time the progressives lacked the political power to make any real changes in the state or federal government, the workplace was also a place that has been†¦show more content†¦During the Great Migration, African Americans began to build a new place for themselves in public life, actively confronting economic, political and social challenges and creating a new black urban culture that would exert enormous influence in the decades to come. 12. ollowing Wilson s de claration of war against Germany, only the socialists continued to actively oppose the U.S. war effort. But in 1918 the Chicago Federation of Labor created a labor party predicated on anti-militarist and anti-imperialist principles and subsequently spearheaded the drive for a national farmer-labor party committed to these same principles. Although the labor party movement proved short-lived, it provided an intellectual legacy for interwar pacifists who sought to promote the peaceful resolution of conflicts outside the framework of the League of Nations.Chicago once again became a center of antiwar agitation during World War II, boasting one of the most active â€Å"America First† chapters in the country. Profoundly influenced by their experiences during World War I, members of the America First organization believed that American democracy could be preserved only by keeping the nation out of European wars. America First bitterly attacked Roosevelt s policies in support of the allies during 1940–41, arguing that they would provoke a German response which would make American entrance into the war inevitable. Although America First was dominated by conservatives,Show MoreRelatedThe Most Important Thing You Remember About A Thesis Statement Essay1040 Words   |  5 Pagesremember about a thesis statement is it gives the reader your opinion and you are entitled to your opinion. You are also giving the reader a new article to read and allow them to give feedback if necessary. This isn t new to me, for I ve done a thesis statement before and received good feedback from fellow classmates. What s different is all of us were focused on once topic and had to come up with our own thesis on that assigned topic. It worked out well. Thesis Statement Number 1: JudgingRead MoreThesis Statement2070 Words   |  9 PagesHOW TO WRITE A STRONG THESIS STATEMENT A WRITING CENTRE HANDOUT 1. UNDERSTAND THE ACADEMIC WRITING TASK You can begin to formulate a good thesis statement only after you have got a solid grasp of the purpose of the assignment. If you’re asked to write a paper in response to a specific assignment question, then your first task is make sure that you clearly understand the academic writing task. Determine which of the following critical thinking skills you are primarily being asked to apply to yourRead MoreThesis Statement1030 Words   |  5 PagesThesis Statement Water pollution has had devastating effects on the environment, which include irreversible effects to the oceans ecosystem, health problems and abnormal conditions. interference of the oceans ecosystem - Plastic storage bags can kill animals in the oceans like dolphins, turtles and whales. It is easy for wildlife to swallow and eventually causes death. * Over 1.5 billion tons of plastic water bottles end up in US landfills each year. It takes over 300 years to degradeRead MoreDeveloping a Thesis Statement607 Words   |  2 Pagesï » ¿Developing a Thesis Statement After choosing a topic, it is important to understand the role a thesis statement in the essay. A thesis statement serves as a road sign that gives  sign  of what the writing  is intended  to tackle; it is the answer to the question asked. A thesis statement is an assertion; it takes a stand announcing the writers position on the topic. It is important for the writer to explore the topic to find a particular narrow subject. It is also important for the writer to knowRead MoreEXAMPLE OF THESIS STATEMENT1195 Words   |  5 Pages Thesis Driven Essay Examples Thesis: William Golding uses symbolism in the form of the conch to represents the concept of society. The boys’ evolving relationship with the conch illustrates that humans, when removed from the pressures of civilized authority, will become evil. 1st TS: In the beginning, the boys view the conch as an important symbol that unites them and gives them the power to deal with their difficult situation. 2nd TS: Gradually, however, the conch becomes less importantRead MoreOutline Of A Thesis Statement Essay1051 Words   |  5 PagesSpecific Purpose: To persuade Thesis Statement: Nurse practitioners should perform primary care and treat minor illness to reduce cost, improve time effectiveness and to reach those who are underinsured or uninsured in community. I. Introduction A. Attention getter: How would you like to get the same or better primary care with lower bill for your healthcare services, improve the community health status or reduce homeless? B. Introduce topic and motivate audience: The healthcare cost hasRead MoreOutline Of A Thesis Statement3601 Words   |  15 PagesThesis / Claim Station: Your claim or thesis statement is the most important part of your argumentative essay. It is the sentence where you state your main argument and outline how you will prove it. There are many ways to structure a thesis statement, but we will work on one specific model: counter-claim-reasons (CCR). Here is an example: Although surveillance cameras may be expensive, schools should install them because they increase safety, reduce vandalism, and keep both teachers and studentsRead MoreAn Introduction With A Thesis Statement1064 Words   |  5 Pages Week 3 - Assignment D. Josh Rhoderick BUS311: Business Law I Instructor: Daniel Malvin Nov 30th , 2015 Final Paper Proposal: Develop an introduction with a thesis statement for the Final Paper: I have been tasked with figuring out if contracts with several large businesses will be governed by common law or the Uniform Commercial Code. Analyze with the owner formed a contract with the businesses, and apply the five essential elements of an enforceable contract. The business is growingRead MoreFinancial Statement Thesis Statement767 Words   |  4 Pagesâ€Å"You can’t connect the dots looking forward. You can only connect them looking backward.† I deeply believe that the Ph.D. program at Carroll School will help my professional experience and academic training come together in the long term - My long term career goal is to become a Finance Professor to teach, conduct research, and produce research publications that would add value and contribute to my field of specialization. At Carroll School, I intend to concentrate in Behavior Finance and ComparativeRead MoreOutline Of A Thesis Statement2067 Words   |  9 Pages Outline THESIS STATEMENT: Individuals who are found guilty of vehicular manslaughter should be sentenced to a minimum of ten years in prison I: Introduction i. Definition of vehicular manslaughter ii. Causes of vehicular manslaughter iii. Sentences for various charges if found guilty II: Body i. The punishments for vehicular homicide according to different states ii. Common penalties if found guilty iii. Why these penalties are not sufficient enough iv. Arguments against justifiable homicide

Alex Sharpes Portfolio Solution Essay - 1231 Words

Context: Alex Sharpe currently invests her children’s educational savings in Vanguard 500 Index Fund, which tracks the performance of Samp;P 500 and is passively managed. However, she is now considering switching her investment strategy to a more active one to achieve better outcomes. Hasbro, a toy manufacturer, and Reynolds, a tobacco firm, have come into Sharpe’s sight and she wants to choose one of them and invest a small proportion of equity funds in it. In order to select a more appropriate investment target, the following issues should be taken into consideration by Sharpe: 1) What are the risk-return characteristics of each stock 2) What are the impacts of either stock to the overall risk-return profiles of the equity†¦show more content†¦2. Perform a regression of each stocks monthly returns on the Index returns to compute a beta for each stock. How does this relate to your answer in question 1? Regression analysis of Reynolds and Hasbro’s returns on market index’s returns shows that Reynolds has a much lower beta coefficient than Hasbro (0.736 compared with 1.42). It is a supporting evidence for our calculation in question 1. Lower beta means that Reynolds is less positively correlated with the market as a whole. So it is obvious that its contribution to overall portfolio’s variance will also be smaller. Take a deeper look at the regression outcome, we found that Intercepts of both stocks have quite large p-value (0.225 for Reynolds and 0.659 for Hasbro). It indicates that those test statistics are not significant enough to reject the null hypothesis that intercept of Reynolds and Hasbro are 0. A more important thing is p-value for beta coefficient. Although Reynolds’s p-value is 0.0285, meaning that null hypothesis that beta is zero will not be rejected for a level of significance at 1%. However, we normally consider a 5% level of significance, so it is enough to reject null hypothesis and Reynolds’s beta is really different from 0. For Hasbro, p-value is far small enough to reject null hypothesisShow MoreRelatedAlex Sharpes Portfolio Solution Essay904 Words   |  4 PagesAlex Sharpe’s Portfolio 1. Returns and Risk Estimate and compare the returns and variability (i.e. annual standard deviation over the past five years) of Reynolds and Hasbro with that of the SP 500 Index. Which stock appears to be riskiest? SP 500 Annualized Expected Return: 6.8920% SP 500 SD (Annualized): 12.477% Reynolds Annualized Expected Return: 22.4980% Reynolds SD (Annualized): 32.446% Hasbro Annualized Expected Return: 14.2060% Hasbro SD (Annualized): 28.114% Reynolds

Osteogenisis Imperfecta Free Essays

string(150) " The height of the child in terms of expected growth, signs of scoliosis or laxity of ligaments, and range of motion of the joints are all important\." Osteogenisis imperfecta (OI) is â€Å"a rare genetic disorder of collagen synthesis associated with broad spectrum of musculoskeletal problems, most notably bowing and fractures of the extremities, muscle weakness, ligamentous laxity, and spinal deformities.† (Binder, 386). Other collagen-containing extraskeletal tissues, such as the sclerae, the teeth, and the heart valves are also affected to a variable degree. We will write a custom essay sample on Osteogenisis Imperfecta or any similar topic only for you Order Now OI has a â€Å"common feature of bony fragility associated with defective formation of collagen by osteoblasts and fibroblasts.† (Smith, 1983, 13) This disease, involving defective development of the connective tissues, is usually the result of the autosomal dominant gene, but can also be the result of the autosomal recessive gene. Spontaneous mutations are common and the clinical presentation of the disease remains to be quite broad. (Binder, 386) OI is most commonly referred to as â€Å"brittle bones†, but other names include: fragilitas ossium, hypolasia of the mesenchyme, and osteopsathyrosis. Osteogenisis imperfecta is still not completely understood, and while there have been advances in diagnosing the disease, treatment is still limited. Osteogenisis imperfecta is the result of mutations in the genes for type I collagen. In the mild dominantly inherited form of OI (type I), † a non-functional allele for the alpha 1 (I) chain halves collagen synthesis,† (Smith, 1995, 169) and is largely responsible for the inheritance. Single base mutations in the codon for glycine causes lethal (type II) OI by wrecking the formation of the collagen triple helix. Types III and IV are the â€Å"less dram- atic outcomes of similar glycine mutations in either the alpha 1 (I) or the alpha 2(I) chains.(Smith, 1995, 169) The clinical signs can be caused from defective osteoblastic activity and defective mesenchymal collagen (embryonic connective tissue) and its derivatives, such as sclera, bones, and ligaments. The reticulum fails to differentiate into mature collagen or the collagen develops abnormally. This causes immature and coarse bone formation and thinning. (Loeb, 755) The signs and symptoms of OI vary greatly depending on the type. The most commonly used classification is the Sillence (type I to IV): Type I is the mildest form of OI and is inherited as an autosomal dominant trait. The sclerae(middle coat of eyeball) is distinctly blue. Type I is broken down into IA and IB — the difference being whether dentinogenesis is present. IA has a life expectancy nearly the same as the general public. The physical activity is limited, and may appear to have no disability at all. The bones have a mottled or wormian appearance, forming small islands. (Isselbacher, 2111) Type II is lethal in utero or shortly there afterbirth. The survivors live from just a few hours to several months. The kayotypes of parents are usually normal. This type is broken down into three subgroups: IIA is characterized by a broad, crumpled femora and continuos rib beading, IIB by minimal to no rib fractures, and IIC by a thin femora and ribs with extensive fracturing. While in the uterus, there is poor fetal movement, low fetal weight, poor ossification of the fetal skeleton, hypoplastic lungs, the long bones of the upper and lower limbs are shortened or deformed, and the head is soft. Intrauterine fractures occur, and parinatal death is usually from intracranial hemorrhage due to vessel fragility or respiratory distress from pulmonary hypoplasia. The bones and other tissues are extremely fragile, and massive injuries occur in utero or delivery. The ribs appear beaded or broken and the long bones crumpled. (Isselbacher, 2111) Type III and IV are intermediate in severity between types I and II. Type III differs from I in its greater severity, and from IV in that it increases in severity with age. It can be inherited as either a autosomal recessive or dominant trait. The sclerae is only slightly bluish in infancy and white in adulthood, although the average life expectancy is 25 years. Type IV is always dominant. With types III and IV multiple fractures from minor physical stress occurs leading to progressive and severe deformities. Kyphoscoliosis may cause respiratory impairment and predisposition to pulmonary infections. â€Å"Popcorn-like† deposits of mineral appear on the ends of long bones. (Isselbacher, 2111) The symptoms of OI tarde (types I, III and IV) can appear when the child begins to walk, and lessens with age. The tendency to fracture decreases and often disappears after puberty. Later in life, particularly during pregnancy and after menopause, more fractures occur. The bones are usually slender with short, thin cortices and trabeculae (fibers of framework), but can also be unusually thin. (Smith, 1983, 136) Narrow diaphysis of the long bones contributes to the fractures and bowing deformities. Scoliosis is common. The haversian cells are poorly developed. The bones lack minerals needed to form bone matrix. Epiphyseal fractures (end of the bone) results in deformities and stunted growth (dwarfism). Osteopenia, the decrease in bone mass, is symptomatic. Other signs of OI include hyperextensibility of the joints — double-jointedness– and abnormally thin, translucent skin. Discolored (blue-gray or yellow-brown) and malformed teeth which break easily and are cavity prone are found in patients Patients with OI have a triangular-shaped head and face, a bilaterally bulging skull, and prominent eyes with a wide distance between the temporal region. (Loeb, 755) Hearing loss by the age of 30-40 is the result of the pressure on the auditory nerve because of the deformity of its canal in the skull, and the development of otosclerosis. Recurrent epistaxis (nosebleeds), bruising and edema (especially at the sight of fractures), difficulty tolerating high temperatures and mild hyperpyrexia are other symptoms. Thoracic deformities may impair chest expansion and the ability to effectively breath deeply and cough. (Loeb, 755) Patients are also more susceptible to infection. In assessing a patient data is needed about the genetic history and birth of the child, as well as a complete development assessment from birth. Vital signs are taken, and periods of increased heart and respiratory rate and elevated body temperature are note- worthy. Skin should be examined for color, elasticity, translucency, and signs of edema and bruising. A description of position and appearance of a child†s trunk and extremities and facial characteristics should be noted. The height of the child in terms of expected growth, signs of scoliosis or laxity of ligaments, and range of motion of the joints are all important. You read "Osteogenisis Imperfecta" in category "Essay examples" Sight and hearing should be tested since there are sensory problems associated with OI. The appearance of the sclerae and tympanic membranes and defects of primary teeth and gums are important. (Jackson, 1699) X-rays usually reveal a decrease in bone density. â€Å"There is no consensus, however, as to whether the diagnosis can be made by microscopy of bone specimens.† (Isselbacher, 2112) DNA sequencing and incubating skin fiboblasts are two ways help diagnose OI. Prenatal ultrasonography is used to detect severely affected fetuses at about 16 weeks of pregnancy. Diagnosis of the lethal type II by ultrasound during the second trimester of pregnancy is by the identification of fractures of the long bones. Compression of the fetal head is seen by ultrasound probe, and low echogeneity of the cranium can be signs of skeletal dysplasia (faulty development of the tissues). Diagnosis is confirmed by postmortem examination including radiography and biochemical studies of cultivated fibroblasts from the fetus. (Berge, 321) Diagnosis by analyzing DNA sequencing can be carried out in chronic villa biopsies at 8-12 weeks. There is no known treatment of OI at this time. Treatment therefore is predominantly supportive and educational. Because of multiple fractures and bruising, it is important to diagnose this disease in order to prevent accusations of child abuse. Treatment of fractures is often challenging because of abnormal bone structure and laxity of the ligaments. Splinting devices are used to stabilize the bones and to protect against additional fractures. Treatment aims to prevent deformities through use of traction and/or immobilization in order to aid in normal development and rehabilitation. Limb deformities and repeated fractures can be corrected by intramedullary rods — telescoping rods that elongate with growth. After surgical placement of the rods, extensive post- operative care is required because greater amounts of blood and fluid are lost. (Loeb, 755) It should be noted that the healing of fractures appear to be normal. (Isselbacher, 2112) Braces, immobilizing devices and wheelchairs are necessary. Physical therapy is important in the treatment of OI. Bone fracture density in unfractured bone is decreased when compared with age-matched controls due to limited exercise, so it is essential to stay as active as possible. Physical therapy is also used for strengthening muscle and preventing disuse fractures with exercises with light resistance, such as swimming. Regular dental visits are necessary to monitor the teeth. Monitoring by opthalmol- ogists for vision and audiologits for hearing is also essential. Radiologists need to examine the structure and density of the bones, and an orthopedist is needed to set fractures and take care of other bone related problems. Counseling and emotional support is needed for both the patient and the family. It is important not to limit a child because of his/her disabilities, and to realize that many victims of this disease live successful lives. Debrah Morris, a successful business woman, and active fighter for disability rights and helping other patients of OI, says, â€Å"If I had the choice to be anyone in the world, I would be exactly who I am. The people I have met, the challenges I have faced, the opportunities that I have been presented — all are directly related to dealing with being a little person with brittle bones.† (Kasper, 53) Many of the symptoms of OI can be confused with those of a battered child. X-rays are used to show evidence of old fractures and bone deformities to distinguish the difference. The Osteogenesis Imperfecta Foundation (OIF) has is a national support group that offers assistance to families in this position and to increase public awareness. The OIF has a medical advisory council, chapters, support groups, regional meetings, biennial national conferences, and parent contacts to help families feeling alone and helpless. They also publish a newsletter, provide literature and videos about OI, and sponsors a fund to support research. Magnesium oxide can be administered to decrease the fracture rate, as well as hyperpyrexia and constipation associated with this condition. (Anderson, 1127) A high-protein, high-carbohydrate, high-vitamin diet is needed to promote healing. A growth hormone has also been administered during childhood, and is shown to substantially increase growth. Treatment with bisphosphorates and related agents has been discussed to decrease bone loss, but no controlled studies have been done. (Isselbacher, 2113) Since there is no cure for oseogenesis imperfecta, appropriate and properly timed rehabilitation intervention is of the utmost importance to ensure that the child is able to function to the best of his/her ability in society. A ten year study that was submitted in 1992 proves this. 25 of 115 children with severe OI were observed since birth or infancy at the National Institutes of Health, MD and the Skeletal Dysplasia Clinic at the Children†s National Medical Center in D.C. One was Type I, two Type II, nine Type III, and thirteen Type IV. They were classified by physical characteristics and functional capacity: Group A consisted of those who were severely dwarfed with large heads and marked bowing , contractures, and weakness of extremities. The highest functional skill expected was independent sitting. Group B was growth deficient, but with a normal sized head. Femoral bowing, scoliosis, and contractures of the hip flexors were characteristics. they were expected to stand and/or ambulate with braces. Group C were less growth deficient, and had good strength, but poor endurance. They had marked joint laxity and poorly aligned lower extremity joints, but were ambulators. (Binder, 386-387) Group A patients were the most severely involved. Most were basically sitters. The majority were totally dependent in their self care. Group B had the potential to become at least short-distance ambulators. These patients had acquired the ability to move to sitting, but had transitional moving problems, such as sitting to standing. All were part- ially independent in their self care. Group C had antigravity strength and 50% had good strength in their extremities. All were physically active and age-appropriately independent, but none were good long-distance walkers. (Binder, 387-388) Progressive rehabilitation of these groups all included posture exercises and active range of motion and strengthing exercises. Group B had additional ROM and posture exercises, as well as Developmental exercises. Group C added coordination activities. Conclusion, â€Å"Management of patients with OI should address the child†s functional needs. Even though the degree of disability may be severe, management should not be limited to orthopedic procedures and bracing. Treatment planning should be considered, but not totally based on genetic, anatomical, and biochemical abnormalities. Our experi- ence suggests that clinical grouping based in part on functional potential can be useful in the appropriate management of children with OI.†(Binder, 390) Independence was stressed in this study, and even patients with limited sitting ability, upper extremity function can be improved to at least minimal independence in self-help skills. Potential ambulators should be helped because, although their ability might not progress past indoor ambulation, walking will make them more independent and may result in increased bone mineralization. Poor joint alignment, poor balance, and low endurance can all be improved with persistent, individualized physical and occupational therapy. For best results, therapy should be started as soon after birth as possible. Mainstreaming school aged children is also important. All of this together leads to â€Å"age-appropriate social development and markedly improved independence and quality of life in the majority of patients.†(Binder, 390) Osteogenesis imperfecta is the most common genetic disorder of the bone. It occurs in about 1 in 20,000 live births, and is equally prevalent in all races and both sexes. The Type I OI has a population frequency of about 1 in 30,000. Type II has a birth incidence of about 1 in 60,000. Types III and IV are less common and may be as high as 1 in 20,000. (Isselbacher, 2111) The occurrence of OI in families with no history or blue sclerae is about 1 in 3,000,000 births.(Smith, 1995, 171) The recurrence risks in families is estimated to be 6 to 10%, but is only estimated because most couples choose not to have any more children. 15 to 20% of patients with OI do not carry the gene for abnormal collagen, making many wonder if there is yet another genetic problem undiagnosed at this time.(Smith, 1995, 172) How to cite Osteogenisis Imperfecta, Essay examples

Australia’s Genocide Tasmanian History †MyAssignmenthelp.com

Question: Discuss about the Australias Genocide Tasmanian History. Answer: The thesis of this essay mainly debates about Australias genocide and gives an insight about it. It basically talks about the Tasmanian history and the question that the writer proposes through this is whether the treatment that happened with Tasmanian history all through the British colonization that has constituted genocide (Taylor, 2013). This book shows the murdering stream of the world. The British colonization almost destroyed all the indigenous organization and it widely shows the conflict between them. Henry Reynolds have acknowledged this and brought out the topic to the people. However there are debates that whether the genocide was done intentionally, though many genocide scholars believe that this genocide was a condign judgment. The writer in his book gives a fact which seeks to again write about their nations foundation. This war took place on the Australian soil. British declared this war for the first time. The first Tasmanian were extremely driven and committed about their ancestral land that none of the obstacles could have stopped their determination. The thesis of Tasmanian genocide has been presented as the history of wars. The genocide is termed as a political notion by misinterpreting the understanding of history. Reynolds has written about this forgotten war with a straightforward remark. Reynolds spoke about the injustice that happened with Aboriginal tribes in Tasmania and however the attitude in Tasmania remained unaffected. Reynolds remarks that there are about 5000 memorials all over Australia in order to remember soldiers who fought in this war (Pihama, 2014). Another key point is that Reynolds mentions that around 5000 settler got killed on this war. Even though all of them were not soldier s like the indigenous warriors who fought as an alternative to guerilla strategy and horror, who attacked several houses and killed families in respect to their own benefits . The Black Wars which took place in Tasmania has an agenda, they were fighting for Australia. In 1835, the population of Aboriginals has vastly reduced due to this war (Lawson, 2014). Aborigines also fought back gradually. Reynolds also mentions that the historical explanation actually differs from the actual reasoning in order to determinate the incidence of genocide. Genocides are an outcome which is based on the assessment of those times. In the further investigation the policy of the colonial government has been shown, that how it was a necessity to examine the steps that has been taken further. The ghost of genocide should be confronted and Reynolds did a just in his book (Docker, 2015). References Docker, J. (2015). A plethora of intentions: genocide, settler colonialism and historical consciousness in Australia and Britain.The International Journal of Human Rights,19(1), 74-89. https://www.tandfonline.com/doi/abs/10.1080/13642987.2014.987952 Lawson, T. (2014).The last man: A British genocide in Tasmania. IB Tauris. https://books.google.co.in/books?hl=enlr=id=eJykAgAAQBAJoi=fndpg=PP1dq=Lawson,+T.+(2014).+The+last+man:+A+British+genocide+in+Tasmania.+IB+Tauris.ots=uKAyO-fOhYsig=N48xNCS5peMPVOvewXw4wd77EyUredir_esc=y#v=onepageqf=false Pihama, L., Reynolds, P., Smith, C., Reid, J., Smith, L. T., Nana, R. T. (2014). Positioning historical trauma theory within Aotearoa New Zealand.AlterNative: An International Journal of Indigenous Peoples,10(3), 248-262. https://journals.sagepub.com/doi/abs/10.1177/117718011401000304 Taylor, R. (2013). Genocide, Extinction and Aboriginal Self?determination in Tasmanian Historiography.History Compass,11(6), 405-418. https://onlinelibrary.wiley.com/doi/10.1111/hic3.12062/full